much better at和 much better in的区别是？

much bette at ------ be much better at 原形 be good at 形容词的比较级，善于某事

much better in ------ do much better in 原形 do well in 副词的比较级，在....干得好

例如： He is much better at English than Chinese. 与语文相比，他更加擅长于英语。（英语比语文好得多）
He does much better in English than Chiese. 与语文相比，他在英语上要做得好得多。

其实，两者的意思是一样的，只是 搭配不一样，与后面的词没有关系。
be good at sth/ doing sth ==== do well in sth/ doing sth

记住：它们是同义词组‘擅长于……’
be good at
=do well in
而good和 well的比较级都是better
记住它们的搭配，相应你知道什么时候用AT，什么时候用IN 了。
如
He is much better in English than she.
He does much better at English than she .

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对，要看后面接的是什么来决定用什么介词。