请各位大虾帮帮忙,小弟急求生物类文献译~~

2024-12-28 20:29:16
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ABSTRACT Curcumin and its structurally related compounds
(curcuminoids), the phenolic yellowish pigments of
turmeric, display antioxidative, anticarcinogenic and hypocholesterolemic
activities. In this study, we investigated the
effects of dietary supplemented curcuminoids [commercial
grade curcumin: a mixture of curcumin (73.4%), demethoxycurcumin
(16.1%) and bisdemethoxycurcumin (10.5%)] on
lipid metabolism in rats. Male Sprague-Dawley rats were
assigned to three diet groups (n 5 6) and fed a moderately
high-fat diet (15 g soybean oil/100 g diet) for 2 wk. One diet
group did not receive supplements (CONT), while the others
were supplemented with 0.2 g curcuminoids/100 g diet
(CUR0.2) or 1.0 g curcuminoids/100 g diet (CUR1.0). Liver
triacylglycerol and cholesterol concentrations were significantly
lower in CUR1.0 rats than in CONT rats. Plasma
triacylglycerols in the VLDL fraction were also lower in
CUR1.0 rats than in CONT rats (P < 0.05). Hepatic acyl-CoA
oxidase activity of both the CUR0.2 and CUR1.0 rats was
significantly higher than that of CONT rats. Furthermore,
epididymal adipose tissue weight was significantly reduced
with curcuminoid intake in a dose-dependent manner.
These results indicate that dietary curcuminoids have lipidlowering
potency in vivo, probably due to alterations in fatty
acid metabolism. J. Nutr. 131: 2932–2935, 2001. 抽象姜黄素和它的结构地相关的化合物(curcuminoids),酚醛淡黄色颜料姜黄,显示抗氧化, anticarcinogenic和hypocholesterolemic活动。 在这项研究,我们调查了饮食被补充的curcuminoids [商品等级姜黄素的作用: 姜黄素(73.4%), demethoxycurcumin混合物(16.1%)和bisdemethoxycurcumin (10.5%)] 在类脂代谢在鼠。 马累Sprague-Dawley鼠被分配了到三个饮食小组(n 5 6)并且哺养了适度地高脂肪饮食(15 g大豆oil/100 g饮食) 2星期。 一饮食小组没有接受补充(CONT),而其他用0.2 g curcuminoids/100 g饮食(CUR0.2)或1.0 g curcuminoids/100 g饮食(CUR1.0)补充了。 肝脏三甘油酯和胆固醇含量是显着低在CUR1.0鼠比在CONT鼠。 血浆三甘油酯在VLDL分数也是低在CUR1.0鼠比在CONT鼠(P < 0.05). CUR0.2和CUR1.0的肝醯CoA氧化酶活动鼠那显着高于CONT鼠。 此外, epididymal脂肪组织重量显著减少了与curcuminoid进水闸以dose-dependent方式。 这些结果在肥腻表明饮食curcuminoids有脂质降低有力体内,大概由于改变酸新陈代谢。 J. Nutr。 131: 2932-2935, 2001年。