前者做宾语 He hates you and me.他讨厌你和我
后者做主语 You and I are good friends.
me是宾格，所以与之相联系的you也是宾格
I 是主格，所以与之相联系的you也是主格
you and me 是宾格
you and I 是主格
比如:
You and I are good friends.
He will take you and me to his party.
一般没有用前者的吧
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