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51问答网 > 比较竞争性抑制与非竞争性抑制的特点,举例说明竞争性抑制作用在药理学上的应

比较竞争性抑制与非竞争性抑制的特点,举例说明竞争性抑制作用在药理学上的应

2025-03-14 23:35:10

推荐回答（1个）

回答1：

竞争性抑制，抑制剂的化学结构与底物相似，能与底物竞争酶活性中心，从而阻碍与底物结合，形成中间产物。
非竞争性抑制，抑制剂与酶活性中心外的必必需集团结合，改变了没活性中心的构象，影响酶对底物的催化作用，使酶—底物—抑制剂复合物不能进一步释放出产物。

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