var reg = /^(?!(\d*|[^\d]*|[^~`\!@#\$%\^&\*\(\)\-_=\+\{\}\[\]\|\\'";\:,<\.>\/\?]*|[~`\!@#\$%\^&\*\(\)\-_=\+\{\}\[\]\|\\'";\:,<\.>\/\?]*|[^\d~`\!@#\$%\^&\*\(\)\-_=\+\{\}\[\]\|\\'";\:,<\.>\/\?]*)$)(?:(?!(.*[~`\!@#\$%\^&\*\(\)\-_=\+\{\}\[\]\|\\'";\:,<\.>\/\?]){2}.*)\S)+$/;
var str = "3&";
console.log(reg.test(str));
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