用这个习惯用法declare the commencement of ...表示“宣布。。。开幕”
为了表示礼貌/显得正式,可以说
Now it's my great honor to declare the commencement of ...International Conference.
或者: I hereby declare the commencement of ...International Conference.
Now I declare the XXX meeting/conference formally begins.
I think it's alright.